P300-based BCI coupled with a robotic hand-orthosis for individual finger movements

This project involved the design, implementation, and evaluation of a P300-based BCI to control a robotic hand-orthosis. The system aims to assist patients with amyotrophic lateral sclerosis (ALS) who are unable to open and close their hands independently. The BCI interface allows users to select one of six targets representing different finger movements. These targets enable the flexion-extension of each finger individually or the simultaneous movement of all five fingers. In our implementation, the BCI system consisted of six options: individual flexion-extension of each finger and simultaneous flexion-extension of all fingers. Visual indicators included five gray circles placed over the fingers to represent individual movements and a circle over the palm to indicate the hand opening and closing. The system was tested both offline and online with eighteen healthy subjects and eight ALS patients to assess its effectiveness.